The SARS-CoV-2 pandemic evidences that promptly detecting which areas and
regions are most susceptible to reinfections is critical to implement adequate containment
policies. Mobility has always been key to viral spreading, but the relatively slow pace of vaccination in the majority of countries,
together with the appearance of new aggressive variants, have forced mitigation measures to rely
primarily on non-pharmaceutical interventions This puts urban centers in
the focus of epidemic surveillance and intervention. Here we show that the organization of
urban flows has a tremendous impact on disease spreading and on mitigation strategies. By studying anonymous and aggregated intra-urban flows in a variety ofcities in the US and other countries, and a combination of empirical analysis and
numerical methods, we demonstrate that the response of cities to epidemic spreading can be
classified into two major types. Centralized cities are
particularly vulnerable to the rapid spread of epidemics. Nevertheless, mobility restrictions in
such types of cities are very effective in mitigating the spread of a virus. Conversely, in
sprawled cities that present many centers of activity, the spread of an epidemic is much
slower, but the response to mobility restrictions is much weaker and less effective.
https://us02web.zoom.us/j/83829318876?pwd=Z2pqbUtIMEV3NUQvU0hpakp0NGtsUT09
