IFISC Seminar on Wednesday Jan 19, 2022 at 14:30 Place: Zoom Seminar Title: Quantitative comparisons between models and data to provide new insights in cell and developmental biology Speaker: Ruth Baker, University of Oxford Abstract: <p>&nbsp;</p> <p style="margin-left:0cm; margin-right:0cm; text-align:start"><span style="font-size:medium"><span style="font-family:Calibri,sans-serif"><span style="color:#000000">Simple mathematical models have had remarkable successes in biology, framing how we understand a host of mechanisms and processes. However, with the advent of a host of new experimental technologies, the last ten years has seen an explosion in the amount and types of quantitative data now being generated. This sets a new challenge for the field &ndash; to develop, calibrate and analyse new models to interpret these data. In this talk I will use examples relating to intracellular transport and cell motility to showcase how quantitative comparisons between models and data can help tease apart subtle details of biological mechanisms.</span></span></span></p> <p style="margin-left:0cm; margin-right:0cm; text-align:start"><span style="font-size:medium"><span style="font-family:Calibri,sans-serif"><span style="color:#000000">References:</span></span></span></p> <ul> <li><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif">T. P. Prescott, K. Zhu, M. Zhao and R. E. Baker (2021).&nbsp;Quantifying the impact of electric fields on single-cell motility.&nbsp;Biophys. J. In press.</span></span></li> <li><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif">J. U. Harrison, R. M. Parton, I. Davis and R. E. Baker (2019). Testing models of mRNA localization reveals robustness regulated by reducing transport between cells. Biophys. J. 117(11):2154-2165.&nbsp;</span></span></li> </ul> <p><br /> <br /> <a href="https://us02web.zoom.us/j/83829318876?pwd=Z2pqbUtIMEV3NUQvU0hpakp0NGtsUT09">https://us02web.zoom.us/j/83829318876?pwd=Z2pqbUtIMEV3NUQvU0hpakp0NGtsUT09</a></p>; Url event:https://ifisc.uib-csic.es/en/events/seminars/quantitative-comparisons-betwee...